Neuron Segmentation Using Deep Complete Bipartite Networks

In this paper, we consider the problem of automatically segmenting neuronal cells in dual-color confocal microscopy images. This problem is a key task in various quantitative analysis applications in neuroscience, such as tracing cell genesis in Danio rerio (zebrafish) brains. Deep learning, especially using fully convolutional networks (FCN), has profoundly changed segmentation research in biomedical imaging. We face two major challenges in this problem. First, neuronal cells may form dense clusters, making it difficult to correctly identify all individual cells (even to human experts). Consequently, segmentation results of the known FCN-type models are not accurate enough. Second, pixel-wise ground truth is difficult to obtain. Only a limited amount of approximate instance-wise annotation can be collected, which makes the training of FCN models quite cumbersome. We propose a new FCN-type deep learning model, called deep complete bipartite networks (CB-Net), and a new scheme for leveraging approximate instance-wise annotation to train our pixel-wise prediction model. Evaluated using seven real datasets, our proposed new CB-Net model outperforms the state-of-the-art FCN models and produces neuron segmentation results of remarkable qualityComment: miccai 201

UG^2: a Video Benchmark for Assessing the Impact of Image Restoration and Enhancement on Automatic Visual Recognition

Advances in image restoration and enhancement techniques have led to discussion about how such algorithmscan be applied as a pre-processing step to improve automatic visual recognition. In principle, techniques like deblurring and super-resolution should yield improvements by de-emphasizing noise and increasing signal in an input image. But the historically divergent goals of the computational photography and visual recognition communities have created a significant need for more work in this direction. To facilitate new research, we introduce a new benchmark dataset called UG^2, which contains three difficult real-world scenarios: uncontrolled videos taken by UAVs and manned gliders, as well as controlled videos taken on the ground. Over 160,000 annotated frames forhundreds of ImageNet classes are available, which are used for baseline experiments that assess the impact of known and unknown image artifacts and other conditions on common deep learning-based object classification approaches. Further, current image restoration and enhancement techniques are evaluated by determining whether or not theyimprove baseline classification performance. Results showthat there is plenty of room for algorithmic innovation, making this dataset a useful tool going forward.Comment: Supplemental material: https://goo.gl/vVM1xe, Dataset: https://goo.gl/AjA6En, CVPR 2018 Prize Challenge: ug2challenge.or

How Well Do Feature-Additive Explainers Explain Feature-Additive Predictors?

Surging interest in deep learning from high-stakes domains has precipitated concern over the inscrutable nature of black box neural networks. Explainable AI (XAI) research has led to an abundance of explanation algorithms for these black boxes. Such post hoc explainers produce human-comprehensible explanations, however, their fidelity with respect to the model is not well understood - explanation evaluation remains one of the most challenging issues in XAI. In this paper, we ask a targeted but important question: can popular feature-additive explainers (e.g., LIME, SHAP, SHAPR, MAPLE, and PDP) explain feature-additive predictors? Herein, we evaluate such explainers on ground truth that is analytically derived from the additive structure of a model. We demonstrate the efficacy of our approach in understanding these explainers applied to symbolic expressions, neural networks, and generalized additive models on thousands of synthetic and several real-world tasks. Our results suggest that all explainers eventually fail to correctly attribute the importance of features, especially when a decision-making process involves feature interactions.Comment: Accepted to NeurIPS Workshop XAI in Action: Past, Present, and Future Applications. arXiv admin note: text overlap with arXiv:2106.0837

Unfooling Perturbation-Based Post Hoc Explainers

Monumental advancements in artificial intelligence (AI) have lured the interest of doctors, lenders, judges, and other professionals. While these high-stakes decision-makers are optimistic about the technology, those familiar with AI systems are wary about the lack of transparency of its decision-making processes. Perturbation-based post hoc explainers offer a model agnostic means of interpreting these systems while only requiring query-level access. However, recent work demonstrates that these explainers can be fooled adversarially. This discovery has adverse implications for auditors, regulators, and other sentinels. With this in mind, several natural questions arise - how can we audit these black box systems? And how can we ascertain that the auditee is complying with the audit in good faith? In this work, we rigorously formalize this problem and devise a defense against adversarial attacks on perturbation-based explainers. We propose algorithms for the detection (CAD-Detect) and defense (CAD-Defend) of these attacks, which are aided by our novel conditional anomaly detection approach, KNN-CAD. We demonstrate that our approach successfully detects whether a black box system adversarially conceals its decision-making process and mitigates the adversarial attack on real-world data for the prevalent explainers, LIME and SHAP.Comment: Accepted to AAAI-23. 9 pages (not including references and supplemental